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Program

November 5th 2017

 

13:00-14:30 REGISTRATION AND POSTER SET UP

14:30-15:00 WELCOME BY HONORARY MEMBERS AND PIERA VALENTI

 

PLENARY SECTION

CHARACTERIZATION AND CONTROL QUALITY OF LACTOFERRIN AND ITS PEPTIDES

15:00-15:30 Bo Lonnerdal (University of California, Davis – USA): Lactoferrin, a multifunctional glycoprotein

15:30-16:00 Hans Vogel (University of Calgary, Calgary – Canada): Structures and functions of different peptides derived from bovine and human lactoferrin

16:00-16:30 Micaela Modiano (European Patent Attorney, Modiano & Partners, Italy, Germany, Switzerland): The Intellectual property: patents for  nutraceuticals (tentative title)

16:30-17:00 Marco Silano (Istituto Superiore di Sanità, Rome – Italy): Characterization and control quality of nutraceutical substances: past, present and future

17:00-17:30 Coffee break

17:30-17:45 Daniele De Sanctis (ESRF Synchrotron, Grenoble – France): A revisit of the three dimensional structure of commercial bovine lactoferrin by x-ray crystallography

17:45-18:15 Piera Valenti (University of  Rome La Sapienza, Rome – Italy): Differences detected among bovine lactoferrin preparations can influence the function and efficacy of commercial bovine lactoferrin

18:15-18:45 GENERAL DISCUSSION

 

19:00 WELCOME PARTY

 

November 6th 2017

 

09:00-13:00  CHARACTERIZATION AND CONTROL QUALITY OF LACTOFERRIN

09:00-09:30 Mamoru Tomita (Dairy Techno Inc., Japan): Perspective on lactoferrin quality for research and application

09:30-09:40 Discussion

09:40-10:10 Hiroyuki Wakabayashi (Morinaga Milk Industry, Japan): Quality control of lactoferrin

10:10-10:20 Discussion

10:20-10:50 Greg Farrant (Tatua Dairy Company, New Zealand): Experience in preserving the activity of lactoferrin  throughout commercial processing.

10:50-11:00 Discussion

11:00-11:30 Coffee break

11:30-12:00 Jean-Paul Perraudin (Taradon Laboratory, Belgium): Industrial purification of lactoferrin: characterization and quality control

12:00-12:10 Discussion

12:10

13:00-14:30 LUNCH
14:30-17:30

  • RECOMBINANT AND TRANSGENIC LACTOFERRINS

 

 

  • LACTOFERRIN GENE EXPRESSION

 

November 7th 2017

09:00-13:00

  • LACTOFERRIN RECEPTORS AND LOCALIZATION

 Nicolas Ostan  (University of Toronto, Ontario – Canada): Mechanism of lactoferrin and lactoferricin sequestration by pathogenic Moraxella bovis

  • LACTOFERRIN AND ITS IMMUNOMODULATING ACTIVITY

 

  • LACTOFERRIN: CELL PROLIFERATION AND DIFFERENTIATION

 

  • LACTOFERRIN AND IRON HOMEOSTASIS

 

13:00-14:30 LUNCH

14:30-16:00

  • LACTOFERRIN AND CNS DEVELOPMENT

 

  • LACTOFERRIN AND OBESITY

 

16:00 POSTER SECTION

 

 

November 8th 2017

09:00-13:00 FORI IMPERIALI OR MUSEO BORGHESE

13:00-15:00 LUNCH

15:00-17:00 ROUND TABLE ON BREAST MILK AND INFANT FORMULA

 

17:00 POSTER SECTION

 

November 9th 2017

09:00-13:00 LACTOFERRIN FUNCTIONS FROM LABORATORY SUGGESTIONS TO CONFIRMATIONS IN ANIMALS AND HUMANS

  • INFECTIOUS DISEASES

Anthony B. Schryvers (University of Calgary, Calgary – Canada): Are bacterial lactoferrin binding proteins viable vaccine targets?

Nidia León Sicairos (University of Sinaloa, Sinaloa – Mexico): Influence of lactoferrin and its peptides against bacterial infections in mice

Jianhua Wang (Chinese Academy of Agricultural Sciences  Beijing, Beijing – China):  Enhancement of killing to Staphylococcus aureus and Salmonella enteritidis and neutralization of lipopolysaccharide 17-residue bovine lactoferricins by cyclization and D-type amino acid substitution: improved activity of Trp/Ala-containing molecules.

Victor Juarez Perez  (Alaxia Company, France): Bacteriostatic and bactericidal activity of lactoferrin.

Francesca Berlutti  (University of Rome La Sapienza, Rome – Italy): Influence of iron and lactoferrin in infection and inflammation processes in  cystic fibrosis mice

  • NEONATOLOGY

Paolo Manzoni (S. Anna Hospital, Torino – Italy): Oral lactoferrin for the prevention of sepsis and necrotizing enterocolitis in preterm infants.

Theresa Ochoa (Universidad Peruana Cayetano Heredia, Lima – Peru):   Long-term outcomes of infants <2000 g after neonatal lactoferrin supplementation

  • PEDIATRICS

Christine Martin-Rouas or Other speaker  (Modilac, France): Lactoferrin and infant health

  • OBSTETRICS

Rosalba Paesano  (University of Rome La Sapienza, Rome – Italy): Anti-inflammatory activity of lactoferrin to prevent and cure pathologies as anemia of inflammation

13:00-15:00 LUNCH

  • GYNECOLOGY

Paola Mastromarino  (University of Rome La Sapienza, Rome – Italy): Lactoferrin and lactobacilli as actors in the scenario of cervicovaginal defense

Simone Filardo (University of Rome La Sapienza, Rome – Italy):  Lactoferrin and lactobacilli against Chlamydia trachomatis genital infections

  • GASTROENTEROLOGY

Eric Nonnecke (University of California, Davis – USA):  A colitis model: investigating the effector functions of lactoferrin and the lactoferrin receptor using knock-out  mouse model

Romina Mancinelli (University of Rome La Sapienza, Rome – Italy): Lactoferrin and its receptors on biliary epithelium

 

20:00 GALA DINNER

 

November 10th 2017

09:00-12:30 LACTOFERRIN FUNCTIONS FROM LABORATORY SUGGESTIONS TO CONFIRMATIONS IN ANIMALS AND HUMANS

  • ORTHOPEDICS

Jillian Cornish (University of Auckland, Auckland – New Zealand):  Bovine Lactoferrin Promotes Bone Regeneration.

  • DENTISTRY

Livia Ottolenghi (University of Rome La Sapienza, Rome – Italy):  Lactoferrin in curing alitosis and other oral pathologies

Valentino Valentini (University of Rome La Sapienza, Rome – Italy): Lactoferrin in healing  the wounds of maxillo facial pathologies.

Other Speakers (to be defined ): Mechanism of action of Lactoferrin in oral pathologies

ONCOLOGY

Hiroyuki Tsuda (Nagoya City University, Nagoya – Japan): Lactoferrin in cancer prevention

12:30-13:00 CONCLUDING REMARKS

13:00-14:00 LUNCH

ARRIVEDERCI TO….